Chronic Pain — 09 November 2013

By Pat Anson, Editor

A single injection of modified Botox could relieve pain from migraines, arthritis and back pain for months without any side effects, according to UK researchers.

Botox is best known for smoothing out facial wrinkles, but its pain relieving qualities are increasingly being recognized.

Researchers at the University of Sheffield have created a modified version of Botox by combining the neurotoxins Clostridium botulinum and Clostridium tetani.

Botuilin is the main ingredient in Botox and works by preventing nerve cells from communicating with muscles – which prevents wrinkles from forming.

Clostridium tetani – also known as the tetanus bug targets the central nervous system and helps ferry the combined toxin to the spinal cord, where it stops pain signals from being transmitted to the brain.

“Currently painkillers relieve lingering pain only temporarily and often have unwanted side effects. A single injection of the new molecule at the site of pain could potentially relieve pain for many months in humans and this now needs to be tested,” said Professor Bazbek Davletov of Sheffield University, who believes the modified Botox could be used to treat several neurological disorders, including chronic pain and epilepsy.

Read more at National Pain Report.


About Author

Pat Anson, Editor

Pat is Editor in Chief of American News Report. He is a veteran journalist and a former correspondent and producer for HealthWeek (PBS), Nightly Business Report (PBS) and other nationally syndicated shows. Pat has won numerous journalism awards, including a Golden Mike award for investigative reporting.

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